Conduct advance care planning with shared decision-making, particularly in patients for whom hematological treatment has uncertain or limited expected benefit, where there is a risk of adverse effects and complications, in patients with comorbid conditions, or those in the end-of-life phase

Rationale:

Early clarification of goals and expectations together with the patient—and, where appropriate, their relatives—supports more patient-centered care pathways, in which the patient’s needs, values, and preferences are incorporated into the decision-making process.

References:

• Temel JS, Greer JA, Muzikansky A, mfl. Early palliative care for patients with metastatic cancer. New England Journal of Medicine. 2010;363(8):733–742.
• Seecof OM, Cronin AM, LeBlanc TW, mfl. Advance care planning for patients with hematologic malignancies: A narrative review. Blood Reviews. 2026;57:101014.
• DuMontier C, Loh KP, Soto-Perez-de-Celis E, mfl. Decision-making in older adults with cancer. Journal of Clinical Oncology. 2021;39(19):2164–2174.