Svineinfluensapandemien sett fra primærhelsetjenesten

The 2009 influenza pandemic in primary care. Clinical manifestations, attitudes and utilisation of servicesKristian Anton SimonsenForskningsgruppen for allmennmedisin ved Institutt for global helse og samfunnsmedisin, Universitetet i Bergen. Kandidaten har også vært faglig tilknyttet Allmennmedisinsk forskningsenhet i Bergen (Uni Research Helse)Disputas UiB 25.3.15

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Background: Primary care plays a major role in the response to a pandemic. The objectives of this thesis were to investigate the outbreak of the 2009 influenza pandemic from a primary care perspective with focus on clinical manifestations, behavioural measures and utilisation of services.

Methods: Cross-sectional questionnaire and clinical observational data from patients in general practice diagnosed with influenza-like illness, and nationwide registrybased studies based on claims data from general practice and out-of-hours services in Norway.

Results: Pandemic influenza in general practice was characterised by symptoms of fever, fatigue, cough and headache of 1 week duration. Hospitalisation was reported in 0.6% of cases and oseltamivir treatment in 39% of cases, but antiviral treatment did not affect the duration of illness. Women reported better adherence to personal protective measures and were more concerned about the side effects of the pandemic vaccine then men. The majority of influenza-like illness consultations took place in general practice as compared to out-of-hours services, however there was a 5.5-fold increase of influenza-like illness consultations in the out-of-hours services during the 2009 pandemic season in comparison to the 2008-9 season. General practice increased its capacity in response to the increased patient surge. Young age was associated with attending out-of-hours services for influenza-like illness as compared to attending the general practitioner. Pregnancy, diabetes and chronic lung disease were significant risk conditions for attending out-of-hours services among patients with influenza-likeillness during the pandemic. Contrary to this, having consultations with the general practitioner before the pandemic was associated with relatively lower use of out-ofhours services in the pandemic period


Paper I: Simonsen KA, Hunskaar S, Wensaas KA, Rørtveit S, Cox R, Njolstad G, Rortveit G. Influenza-like illness in Norway: clinical course, attitudes towards vaccination and preventive measures during the 2009 pandemic. Fam Pract 2012;29:139-46. The article is not available in BORA due to publisher restrictions. The published version is available at:


Paper II: Simonsen KA, Hunskaar S, Sandvik H, Rortveit G. Capacity and adaptations of general practice during an influenza pandemic. Plos One 2013;8:e69408. The article is available at:


Paper III: Simonsen KA, Hunskaar S, Sandvik H, Rortveit G. Primary care utilisation among patients with influenza during the 2009 pandemic. Does risk for severe influenza disease or prior contact with the general practitioner have any influence? Fam Pract 2015;32:56-61. The article is not available in BORA due to publisher restrictions. The published version is available at: