Uke 31: ITP - clinical practice

ITP i klinisk praksis.
Gratulerer og av med hatten, til Waleed, for en flott artikkel i NEJM.
Immune Thromobocytopenia - NEJM

Immune thrombocytopenia (ITP) is an autoimmune disease characterized by isolated thrombocytopenia. Patients may be asymptomatic at presentation or they may present with mild mucocutaneous to life-threatening bleeding. Although only 5% of patients with ITP present with severe bleeding,1 bleeding leading to hospital admission within 5 years after diagnosis develops in approximately 15%.2 Irrespective of bleeding problems, patients with ITP often report fatigue and impaired health-related quality of life.3 The risk of venous thromboembolism is twice as high among patients with ITP as among persons in the general population; the management of venous thromboembolism may be especially problematic given the concomitant risk of bleeding.4